Theophylline is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian. Bronchodilatorsto reduce bronchoconstriction and relieve airflow limitation. It should be used with caution in pets with abnormal heart rhythms, seizures, stomach ulcers, hyperthyroidism, kidney, liver, or heart disease, severely high blood pressure, severely low blood oxygen levels, … There are a number of other possible drug interactions with theophylline, including: Allopurinal, beta-blockers, propanolol, cimetidine, calcium channel blockers, corticosteroids, thiabendazole, exogenous thyroid hormone, macrolide antibiotics, flouroquinolones antibiotics, barbiturates, rifampin, carbamazine, charcoal, phenytoin, ketoconazole, beta-agonists, lithium, pancuronium, propofol, isoniazid, furosemide, ephedrine, isoproterenol, halothane, and ketamine. Possible Side Effects May cause loss of appetite, nausea, vomiting, diarrhea, or nervousness at the beginning of treatment. Metronidazole: risk of neurologic side effects. The dosage and administration of Theophylline varies according to the size and breed of the pet being treated, and the type and severity of their illness, but typically, the drug is taken every 6, 8, 12, or 24 hours. These drugs are airway dilators, opening the bronchial tubes. Discussion Guide for Pet Owners and Veterinarians, Medication Information for Pet and Horse Owners. In most cases, the side effects can be managed through … If side effects appear or if unusually high doses are required, serum theophylline should be monitored. This drug is registered for use in humans only. Theophylline is appropriate for use on cats and dogs when it is administered under the guidance of a veterinarian. ©Copyright 1999 - 2021. The effects of theophylline on psychomotor functioning and school performance have been examined and have generally shown no significant negative on learning or behavior. Until more is known about cimetidine interactions, alternative H 2 blockers such as ranitidine, famotidine, or nizatidine (which are not P450 inhibitors at … It is typically taken by mouth for the long-term control and maintenance of asthma, COPD (including emphysema and chronic bronchitis), and other chronic lung diseases. It is approved for use in the United States for dogs with congestive heart failure (CHF) caused by either dilated cardiomyopathy or mitral valve disease. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. No claims are made as to the safety or efficacy of mentioned preparations. Log in with your secure digital account and gain instant access to the industry’s largest formulary of compounded medications – 24 hours a day, 7 days a week. This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug. Be sure to discuss any side-effects with your veterinarian immediately. Theophylline has been used as an adjunct treatment in heart failure. Theophylline can be used with corticosteroids and may allow using a lower dose of the corticosteroid. Seizures can occur if the animal receives a significant overdose. The most common side effects are central nervous system stimulation and gastrointestinal upset; particularly nausea and vomiting. On 3 separate days, theophylline was infused to defined steady-state concentrations (0, 7.5, and 15 … For dogs, theophylline is dosed at 3 to 5 mg per pound (6 to 10 mg/kg) three times daily; higher doses may be prescribed with the twice-daily extended action preparations. Dr. Evan Ware is a veterinary practitioner in Phoenix, Arizona. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. Theophylline Side Effects Theophylline is a bronchodilator, which a veterinarian may prescribe for your pooch to help relax her airways. Other side effects that are likely to occur are vomiting, diarrhea, increased palpitation, a rise in body temperature, increased heart rate, skin rashes etc. Atenolol is a beta adrenergic blocker that is used in veterinary medicine to treat supraventricular tachyarrhythmia, premature ventricular contractions (PVC’s), and systemic hypertension. Allow plenty of fresh water to drink. A diet rich in fat increases the toxicity of this medication. Theophylline should be used with care in patients that have been diagnosed with kidney disease, liver disease, heart disease, stomach ulcers, hyperthyroidism, or hypertension. Federal law restricts this drug to use by or on the order of a licensed veterinarian. The medication has certain side effects such as irritation in the stomach, nervous system excitement etc. While the drug may help her breathe easier, it can cause her to become nervous and restless, increase her heart rate or cause an abnormal heart rhythm, warns VeterinaryPartner.com. with the diplomatic agreement of what the cats will be used for) and were of good health. Another sample should be drawn 5-10 hours after administration of Nuelin SR when the theophylline level is at a maximum. Theophylline is used in feline asthma and in chronic bronchitis in dogs. Ordering compounded medications is easier than ever. Other less serious side effects … Give this medication to your pet exactly as your veterinarian prescribes. Such drugs include certain antibiotics, phenobarbital, propranolol, caffeine, acetaminophen and furosemide. Side effects usually subside with dosage adjustments and/or continued therapy. High blood pressure 4. Due to the way this drug is metabolized, the dose for your pet will be calculated based on their ideal or lean body weight. Please select your state below. This page details the usage of theophylline for dogs suffering with asthma. Blood samples for monitoring should be drawn immediately before administration of the morning dose when the serum theophylline level is lowest. It can be stored at room temperature, but should be kept away from light, heat, and moisture. Theophylline has been shown to cause stomach irritation and nervous system stimulation. Initially, each individual's pharmacokinetic parameters for theophylline were determined. The medicine works by relaxing the smooth muscle surrounding the … It should be used with more caution in animals with abnormal heart rhythm, and in those with a history of seizures. Some are considered “extended release” preparations, exhibiting a longer duration of effect. Commonly reported side effects include: acid-base imbalance. … 405 HERON DRIVE SUITE 200 • SWEDESBORO, NJ 08085-1749 | © 2004-2017 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED. Methylxanthine drugs, such as theophylline, work by inhibiting enzymes (phosphodiesterases) inside of cells and promoting dilation of smooth muscle in bronchial tubes and blood vessels. Theophylline is available in both an oral and an injectable form. Commonly reported side effects of theophylline include: acid-base imbalance. Theophylline is used in situations that require dilation of the airways. Most commonly, the side effects of Theophylline include central nervous system excitement, vomiting, fever, rash, and heart palpitations. Theophylline should be used with caution in animals with severe heart disease, abnormal heart rhythms, kidney or liver impairment or high blood pressure. Potential side effects: Restlessness or caffeine-type jitters.Mild stomach upset, racing heart with abnormal heart rhythm (not all patients) Diuretic effect in some patients (increased thirst and urination) Seizures and heart rhythm problems can occur with severe intoxication. Theophylline has been shown to cause stomach irritation and nervous system stimulation. Theophylline is very effective at relaxing the muscles surrounding the airway and clearing out the mucus that can make breathing more difficult. Shipping Carrier Delays Expected - We have been advised by our carriers that packages may require 2 or more additional days for standard delivery, because of the Corona Virus. Among the drugs and substances that can interact with Theophylline, the mo… Zinc Poisoning in Dogs and Cats. Winter Holiday Hazards for Pets. The drug should not be prescribed to pregnant or lactating patients or horses. However, alter the dosage to control much of these symptoms. May cause seizures at high doses. Theophylline. Make sure that your cat does not eat fatty meals while taking Theophylline. It is also available as a 80 mg/15 ml or 150 mg/15 ml syrup. Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or … Less-common but more-serious side effects include abnormal heart rhythm and seizures. See the full Symbicort side effects document. Fear of Noises in Dogs and Cats. Rat Poison's Effect on Dogs and Cats. 's Animal Poison Control Center at 888.426.4435. Read the labeling or ask your pharmacist for the storage requirements of the prescription you receive. Other less serious sid… Human formulations: Theo-Dur® (Key Pharmaceuticals) and various generic brands are available. Side-effects, further information. Always bring the prescription container with you when you take your pet for treatment. Some states restrict the information we may provide about controlled substances. It is very well-absorbed after oral administration. Theophylline not only helps the patient breathe easier, but it also helps prevent future breathing constrictions. Stop giving theophylline and call your veterinarian at once if any of the following side effects occur seizures severe nausea and vomiting, and restlessness coughing up blood or vomit that looks like coffee grounds urinating more than normal. Safe Gardening for Dogs and Cats. Theophylline has known interactions with several different drug classes, including certain antiarrhythmics, anti-seizure drugs, certain beta-blockers, as well as cimetidine, digoxin, disulfiram, fluvoxamine, interferon, isoproterenol, and many others. It helps clear out mucus build-up by increasing the movement of cilia within the airway. The drug is structurally similar to caffeine, which works as a central nervous system stimulant. Keep this and all drugs out of reach of children. The drug should be used with caution in animals with liver or heart disease. Side effects Side effects when using theophylline include nausea, vomiting, diarrhea, central nervous system excitement, fever, rash and palpitations. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. Humans are sensitive to these side effects … Isa and others published Effect Of Theophylline On Blood Pressure Of Normotensive Cats Pre-Administered With Adrenaline | Find, read and cite all … Other potential adverse effects include nausea, vomiting, and diarrhea. If any of the following serious side effects occur, stop giving Theophylline ER and seek emergency veterinary medical attention: an allergic reaction such as difficulty breathing, swelling of the lips, tongue, face, or hives. Theophylline works by relaxing the smooth muscles of the airway… Side effects when using theophylline include vomiting, central nervous system excitement, fever, rash and palpitations. Theophylline is an oral medication used to treat asthma and other lung diseases. See below for a comprehensive list of adverse effects. Theophylline is used off label to treat cough caused by bronchoconstriction. All Rights Reserved. Aminophylline may interact with other medications. However, if the patient experiences prolonged vomiting or diarrhea, or she develops hives or other signs of an allergic reaction, then she should be taken to the veterinarian as soon as possible. If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A. Theophylline should not be used in patients allergic to this class of medication. The drug works best when it is taken on an empty stomach and at least an hour before or two hours after eating. Stop giving theophylline and call your veterinarian at once if any of the following side effects occur: seizures, severe nausea and vomiting, and restlessness, coughing up blood or vomit that looks like coffee grounds, urinating more than normal. In most cases, the side effects can be managed through dosage adjustments, and this will usually cause them to gradually subside over time. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with theophylline. If they do not, or your pet has a rapid heartbeat, or an increase in appetite, drinking or urination, contact your veterinarian. The … Theophylline, also known as Theo-Dur®, belongs to the class of drugs known as smooth muscle relaxants, affecting the respiratory muscles in dogs and cats. Sometimes theophylline is used in addition to other medications to achieve or improve symptom management. The cats, each weighing 1.6kg and 1.3kg respectively, were brought to the laboratory from a domestic home with the consent of the owner (coupled www.iosrjournals.org 116 | Page Effect Of Theophylline On Blood Pressure Of Normotensive Cats Pre-Administered With Adrenaline. Theophylline is available in a range of formulations, including tablet, capsule, and oral liquid. If using the long acting form, do not chew, crush or allow to dissolve on food. Theophylline is a bronchodilator that is prescribed by veterinarians to help relax the muscles in a patient's lungs and chest so she can breathe easier. Anxiety and restlessness are common side effects of treatment in dogs. Like many other drugs in veterinary medicine, this drug is not FDA-approved for use in animals and is not available from a veterinary pharmaceutical manufacturer. This content is intended for counseling purposes only. It can also be given intravenously (into a vein) for treatment for severe asthma attacks or COPD exacerbations. Safe and Toxic Garden Plant Images. Kidney problems 5. Theophylline and aminophylline: theophylline toxicity. Body Language of Cats . The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. Some clinicians will start an animal on a lower dose and increase the theophylline to the therapeutic dose after the first week. 4. Potentially serious hypokalaemia may result from beta 2-agonist therapy. However, the patient can still experience side effects with this drug. … Behavior. His areas of interest include orthopedic medicine and surgery, veterinary oncology and chemotherapy, and general and advanced soft-tissue surgery. Levalbuterol is available in a nebulizer solution or a metered dose inhaler, but is not commonly prescribed for cats. Theophylline is considered a component of a treatment plan. However, the patient can still experience side effects with this drug. Seizures can occur if the animal receives a significant overdose. Do not use in pregnant or lactating animals. Wash your hands after giving your pet this medication. Beta blockers improve cardiac performance indirectly by reducing the heart rate; prolonging diastole, which allows more time for ventricular and coronary arterial filling. If so, contact your veterinarian immediately. It is highly recommended not to administer this drug to your cat if he or she suffers from: 1. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Side-effects of theophylline are often dose dependent and include anorexia, nausea, emesis and headache. Instead, it is compounded by a compounding pharmacy. It is extremely important to administer the medication exactly as prescribed by the veterinarian. Toxic and Non-toxic Plants. See the full Advair Diskus side effects document. Warfarin, propranolol, diazepam, midazolam, many others. Heart disease 3. Information such as dosages and side effects are contained within this article. If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222. Very young and very old animals may metabolize this drug more slowly. Find everything you need to know about Theophylline (Theo-24), including what it is used for, warnings, reviews, side effects, and interactions. He received both his undergraduate degree in microbiology and his Doctorate of Veterinary Medicine from The Ohio State University. Most commonly, the side effects of Theophylline include central nervous system excitement, vomiting, fever, rash, and heart palpitations. Learn who it’s for, how it works, its side effects, warnings, and more. Do not give this medication to a person. Do not double dose to catch up. Arrhythmia 2. When administering Theophylline in tablet form, the tablet needs to be swallowed whole, not chewed. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Cats: 2 mg/lb every 8-12 hours. The … Anxiety and restlessness are common side effects of treatment in dogs. 4 Theophylline is … Adverse Effects [please contact CVCA should any of these symptoms be noted] Caffeine like side effects (anxiety, restlessness, panting) Decreased appetite, vomiting or diarrhea; Increased heart rate and risk for arrhythmias; Small increased risk for … Each of these drugs is properly called a methylxanthine. All product and company names are trademarks™ or registered® trademarks of their respective holders. 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